SERVICES

We are offering support and/or consulting in the following areas on fee-for-service basis:

• Protein Expression and Purification
• Crystallization
  - X-CHIP Technology Approach
  - Conventional methods
• Diffraction Data Acquisition
  - X-CHIP Technologies Approach
  - Conventional synchrotron X-ray diffraction data collection and processing
• Crystal Structure Determination
  - De novo crystal structure determination
  - High-throughput complex crystal structure determination
  - Fragment-based screening
• Computational Technologies
  - Target analysis
  - In silico Structure-based drug design
  - Virtual screening, both structure-, ligand- and fragment-based
  - Target-based small molecule- and fragment-based library design for HTS
  - Focused library design to support Hit-to-Lead and Lead Optimization efforts
  - Overcoming off-target activity issues
  - SAR Analysis, data mining and data analysis
  - Optimization of physical and ADMET properties