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SERVICES

We are offering support and/or consulting in the following areas on fee-for-service basis:

  • Protein Expression and Purification
  • Crystallization
    - X-CHIP Technology Approach
    - Conventional methods
  • Diffraction Data Acquisition
    - X-CHIP Technologies Approach
    - Conventional synchrotron X-ray diffraction data collection and processing
  • Crystal Structure Determination
    - De novo crystal structure determination
    - High-throughput complex crystal structure determination
    - Fragment-based screening
  • Computational Technologies
    - Target analysis
    - In silico Structure-based drug design
    - Virtual screening, both structure-, ligand- and fragment-based
    - Target-based small molecule- and fragment-based library design for HTS
    - Focused library design to support Hit-to-Lead and Lead Optimization efforts
    - Overcoming off-target activity issues
    - SAR Analysis, data mining and data analysis
    - Optimization of physical and ADMET properties